Search on: RETINOBLASTOMA NUCLEAR PHOSPHOPROTEIN P105 RB 
Descriptors Found: 1
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Descriptor English:   Retinoblastoma Protein 
Descriptor Spanish:   Proteína de Retinoblastoma 
Descriptor Portuguese:   Proteína do Retinoblastoma 
Synonyms English:   Rb Gene Product
Rb Protein
Rb1 Gene Product
Retinoblastoma Nuclear Phosphoprotein p105 Rb
Retinoblastoma Nuclear Phosphoprotein p105-Rb
p105 Rb Protein
p105-Rb Protein  
Tree Number:   D12.776.260.704
D12.776.624.776.745
D12.776.660.807
D12.776.744.770
Definition English:   Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein. 
Indexing Annotation English:   /biosyn /drug eff /physiol /ultrastruct permitted
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29109 
Unique Identifier:   D016160 

Occurrence in VHL:
 

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